The vet students meet for the first time and travel 7 hours to the remote clinic. We learn about their fears and insecurities -- fear of failure and the weight of responsibilities ahead. The resident vet, Dr. Greg, helps them muddle through the first real cases of their young careers. At the end of the long day, the vets are called out to an emergency – a lion cub has escaped out a local wildlife park, placing itself and the community in danger. The vets form a search party in the pitch black bushveld. Can they find the nursing cub before certain death from dehydration? Can Agatha redeem herself after a disastrous start at the clinic?

The vets get situated in their dormitory accommodations. Dr. Greg deliberately pairs them according to their differences. Vets need to learn to work with colleagues and clients different from themselves. The students dive into more cases. Drew and scared Agatha must dart a wild warthog to help treat its painfully swollen leg and Niven is punished by Dr. Greg for some immature antics. Niven has to care for a dying goat and sides with Delarey’s treatment suggestion over Roxanne’s. Will the goat survive? Later as a group they run a cattle call where over a 1000 local cows take a medicated plunge bath to prevent disease and parasites. The vets have never experienced anything like this before as they have to deal with the chaos around them. The day is reflected on as the group enjoys a bonfire, but there are growing tensions amongst the group. Will they fracture or be brought closer together by their differences?

Roxanne let her puppy case, ‘Ripple’ stay overnight at the dorm. The group – especially her roommate Charlotte - is critical of this. Not only is she using the dog as a social crutch, it’s highly unprofessional to become so attached to a patient. The students get to accompany a research team to conduct a study on Africa’s biggest mammal – an adult elephant. But the routine research soon becomes a high intensity emergency situation. Agatha and Tina have their first spat. At any given time, Niven is either teasing Roxanne or dismissing her medical opinions. Delarey takes on helping Drew with the language. Charlotte is shocked to hear the news about her first case, an ailing calf. And Tina is brought a puzzling case of a goat with neurological problems. Her pragmatic mind jumps to ‘euthanize it.’ Niven and Agatha face ‘The Killer Cow’ and petite Agatha must face her fear of cattle head on. The day ends at a local festival where the group makes foreigners Tina and Drew eat dried chicken feet – a local snack. One foot ends up in Niven’s bed that night! Who’s the prankster?

Dr. Greg forces the students to attend a local Heritage Festival, but their day off turns emotional when they experience South African dance and customs. Roxanne faces her toughest challenge yet: performing orthopedic surgery on her adopted puppy, Ripple, possibly requiring amputation. Delarey is shockingly replaced as her assistant and later channels his frustration into leading a dangerous effort to lift a weak cow before it is slaughtered, sparking conflict among the group. Meanwhile, Tina doubts her instincts as her goat improves, and Agatha and Niven race to save a sick calf before it dies, testing Agatha’s resilience.

Tina faces heartbreak when her goat worsens and the owner, on religious grounds, refuses euthanasia, leaving her emotionally shattered. Agatha questions her future as a vet, while Roxanne’s fear of lizards is exposed and she is sent to the sanctuary, straining her relationship with roommate Charlotte. Charlotte’s first operation, a dog castration, is threatened by her fainting at blood, and Delarey’s risky drug choice could leave the dog waking mid-surgery. Roxanne steps up to resolve a crisis, earning newfound respect, while a night out reveals Niven making a move on Charlotte.

Dr. Greg punishes the hungover group by assigning clinic cleaning, with Niven and Drew stuck scrubbing the dip tank, leaving Drew furious after traveling from America. Tina is stunned when her dying goat miraculously tries to stand, challenging her faith in science. Dr. Greg tests Agatha with a difficult calf birth, hoping success will restore her confidence. Drew performs a risky puppy blood transfusion, while Niven and Jonathan help capture a dangerous reedbuck. The students also assist at a baboon sanctuary, and Charlotte is bumped into Niven’s spot for a tense castration surgery. Just as Agatha regains motivation, she learns she failed her exams and must leave the residency.

Drew and Agatha have to deal with a dog with a broken leg brought in by a group of youngsters with no money. Will Agatha stand up to Drew who has decided to send them away to find money, by insisting the dog stays at the clinic? Roxanne and Charlotte treat a tragically emaciated dog and are very critical of the owner. They give him firm lesson in dog care, but wonder if any of it sank in. The group runs another cattle dip where the owners take to whipping the cows more than ever. Drew is extremely upset. His frustrations threaten to boil over as his inability to communicate with the owners and his frustrations with the environment reach boiling point. A dying puppy is brought to the clinic. It isn’t breathing. Dr Greg shouts instructions to the young vets but the emergency case has caught them by surprise – they struggle to find the necessary equipment and drugs. Will the puppy survive? Everyone in the group is at an all time low. Dr. Greg takes the group to a beautiful waterfall in the mountains in attempt to reenergize them.

Charlotte grows frustrated with a dog owner who avoids responsibility, and she and Roxy visit his home to check on his other animals. Meanwhile, Drew and Agatha worry when a broken-leg puppy’s owners fail to return with payment; Agatha realizes she was right to want to keep the pup and vows not to doubt herself again. She faces a new challenge when a dying puppy arrives with no owner willing to pay—will she stand up for it? Jonathan confronts his fear of snakes, and Drew is inspired to fight animal cruelty in Africa. Roxanne celebrates her parents adopting Ripple, but Dr. Greg shocks her by refusing to let the puppy leave the community.

Dr. Greg sets up a darting competition – the winner gets to dart a zebra on an upcoming case. Delarey, the hunter, is shocked when Roxanne, hits a bulls eye! Can he do the same? The zebra darting is an exciting and dangerous event because while getting towards the zebra a herd of buffalo move in and at one point Delarey has to fight off a feisty Wildebeest. Later, the local Chief invites the students to a community feast. The students observe the meat preparation at the slaughter house. The visit brings up issues of animal welfare, hygiene and cultural myth being taken as fact. Who is prepared to eat the meat? Who is going to decline and risk insulting the Chief? Agatha’s attachment to the little puppy Milo grows and fears returning the puppy to a bad situation. Having finally backed herself, this case has the potential to go horribly wrong and the consequences could be devastating for the sensitive vet’s self-confidence. Jonathan and Niven react to an emergency case – a Jack Russel dog has been bitten by a Black Mamba, a highly poisonous snake. For the first time we see Jonathan react emotionally to a case and Niven feel the real weight of his responsibility as a vet.

During a rabies vaccination campaign, Niven struggles to vaccinate a nervous dog, knowing an unvaccinated animal endangers the community. When the group visits a cheetah rehabilitation farm, Tina and Niven must manage the clinic alone, and Tina faces conflict when barred from treating a cow due to local beliefs. Back at the clinic, Niven persuades an owner to fund a castration instead of euthanasia after her dog bites her son, risking his newfound responsibility. Tina must decide whether to treat a gunshot wound filled with maggots or euthanize the injured dog. Agatha teaches puppy care, while Niven faces the possibility of more trouble with Dr. Greg.

Tina is haunted by doubt over her decision about Bobby, and the other students wonder if her goat case influenced her choice. Meanwhile, debates over hunting and animal welfare escalate until Tina threatens to call the police. At a witchdoctor inauguration, Agatha is disturbed by a trance ritual and questions whether tradition and modern values can coexist. Jonathan and Niven face a risky reedbuck relocation, deepening Jonathan’s doubts about his career. Delarey suspects a dead cow was poisoned, but then fears it may be anthrax, a deadly disease that could endanger everyone who handled the carcass. As the group races to confirm the diagnosis, tensions flare and blame is thrown at Dr. Greg for not acting sooner.

Delarey races to Kruger Park with slides to confirm whether the cow died of anthrax. Agatha checks on Milo, wondering if the family followed her advice or if she must remove him. Charlotte grows frustrated vaccinating hunting dogs and questions her future as a community vet. Jonathan must confront his fear of snakes to operate on a Cape cobra, while Drew returns to see if farmers adopted his cattle-handling advice. Tina challenges donkey owners over poor conditions and must decide whether to gain their trust. When a rhino escapes a park fence, Dr. Greg asks Roxanne to join him in a microlight search, forcing her to choose between her parents’ wishes and her own courage.

Dr. Greg spots the rhino from the microlight. The students rush in. Time is against them as poachers could arrive at any moment. The dart gun does not work and they have to get another one wasting more precious time. Delarey has to race to the ascending chopper and hand then the second gun whilst airborne. It’s a tricky maneuver. There is much confusion as to where the rhino has fallen. The vehicle carrying the experienced vet breaks down. Dr. Greg is delayed and unable to reach the rhino. How will the students manage without him and the more experienced team? The episode and season ends with their final morning of the students’ residency. Emotions run high as Dr. Greg wishes his students the best of luck with their careers. But it’s the tears of one vet in particular that come as a surprise. The tears say it all: it’s been an incredible journey of self-discovery. It’s time for them to bid farewell to a mentor and a community that has taught them so much. Their journey to the frontier has ended, but their journey as a vet has only just began.